Selected peer-reviewed publications: 

Gabriely G*, Wurdinger T*, Kesary S, Esau CC, Burchard J, Linsley P, Krichevsky AM.
MiR-21 promotes glioma invasion by targeting MMP regulators (Mol Cell Biol, 2008, in press). *equal contribution.

Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah, K.
MIcroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res 67(19):8994-9000 (2007).

Krichevsky AM*, Sonntag KC*, Isacson O, Kosik KS.
miRNAs modulate neuronal and glial differentiation of mouse ES cells. Stem Cells 24(4):857-64 (2006). *equal contribution.

Monticelli S, Ansel KM, Xiao C, Socci ND, Krichevsky AM, Thai TH, Rajewsky N, Marks DS, Sander C, Rajewsky K, Rao A, Kosik KS.
MicroRNA profiling of the murine hematopoietic system. Genome Biol. 6(8):R71. Epub 2005 Aug 1.

Chan J*, Krichevsky AM*, Kosik KS.
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 65(14):6029-33 (2005). *equal contribution.

Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G.
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons.  Proc. Natl. Acad. Sci. U S A. 101(1):360-5 (2004).

Kao SC, Krichevsky AM, Kosik KS, Tsai LH. 
BACE1 suppression by RNA interference in primary cortical neurons. J Biol Chem, 279(3): 1942-9 (2004).

Krichevsky AM, King K, Donahue CP, Khrapko K, Kosik KS. 
A microRNA array reveals extensive regulation of microRNAs during brain development.  RNA, 9(10): 1274-81 (2003).

Krichevsky AM, Kosik KS. 
RNAi functions in cultured mammalian neurons.  Proc. Natl. Acad. Sci. U.S.A., 99(18):11926-9 (2002).

Krichevsky AM, Kosik KS.  Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation. Neuron, 32(4):683-96 (2001).

Vaisman B, Meyroin-Holtz EG, Fibach E, Krichevsky AM, Konijn AM.
Ferritin expression in maturing normal human erythroid precursors.  Br. J. Haematol. 110(2):394-401 (2000)

Krichevsky A, Metzer E, Rosen H.
Translational control of specific genes during HL-60 cellular differentiation. J. Biol. Chem., 274(20):14295-14305 (1999). 

Rosen H, Krichevsky A, Polakiewicz R, Benzakine S, Bar-Shavit Z.
Developmental regulation of Proenkephalin gene expression in osteoblasts.  Mol. Endocrinol., 9:1621-1631 (1995).

REVIEWS
Satterlee J, Barbee S, Jin P, Krichevsky AM, Salama S, Schratt G, and Wu DY.
Non-coding RNAs in the Brain. J. Neuroscience, 27(44):11856-9 (2007).

Krichevsky AM.
MicroRNA Profiling: From Dark Matter to White Matter, or Identifying New Players in Neurobiology. TheScientificWorldJOURNAL (7) 155-66 (2007).

Kosik KS, Krichevsky AM.
The Elegance of the MicroRNAs: A Neuronal Perspective. Neuron.  47(6):779-82 (2005).

Kosik KS, Krichevsky AM.
A model for local regulation of translation near active synapses. Sciense's STKE 2005(300):tr25 (2005).

Kosik KS and Krichevsky AM. 
The Message and the Messenger:  Delivering RNA in Neurons.  Science's STKE (126):PE16, Review (2002).

Rosen H, Krichevsky A, Bar-Shavit Z. 
The enkephalinergic osteoblast.  J Bone Miner. Res., 13(10):1515-1520, Review (1998). 

BOOK CHAPTERS
Krichevsky AM, Kao S-C, Tsai LH,  Kosik KS.
MiRNAs in the brain and the application of RNAi to neurons. RNA Interference Technology: From basic biology to drug development. Cambridge University Press, (2004).

 

Home

Research

People

Publications

Directions